Baltazar Nunes 

 

Contactos

Escola Nacional de Saúde Pública, Av Padre Cruz, 1600-064 Lisboa (+ 351 21 7512100; bnunes@ensp.unl.pt).

Instituto Nacional de Saúde Dr. Ricardo Jorge, Av Padre Cruz, 1649-016 Lisboa (+ 351217526487; baltazar.nunes@insa.min-saude.pt).

 

Áreas de Interesse

Bioestatística e Epidemiologia, Métodos de amostragem, Estudos Observacionais de base populacional, Inquéritos Nacionais de Saúde com Exame Físico, Estudos de efetividade/impacto de vacinas e programas de vacinação, Epidemiologia das doenças infeciosas.

 

Ensino

Professor Auxiliar convidado na Escola Nacional de Saúde Pública.

Docente da disciplina de Estatística e colaborador nas disciplinas de Epidemiologia e Investigação Epidemiológica, nos Cursos de Especialização em Saúde Pública, Medicina do Trabalho, Administração Hospitalar e programa de Doutoramento.
Orientador de diversos trabalhos de mestrado e trabalhos finais do Curso de Especialização em Saúde Pública.

 

Investigação (projectos em curso)

2015-2018 – I-MOVE+ Integrated Monitoring of Vaccines Effects in Europe: a platform to measure and compare effectiveness and impact of influenza and pneumococcal vaccines and vaccination strategies in the elderly. Horizon 2020 grant 634446-2 PHC-17-2014
2013-2016 – “Improvement of epidemiological health information to support public health decision and management in Portugal – towards reduced inequalities, improved health and bilateral cooperation”[1º Inquérito Nacional de Saúde com Exame Físico] INSA, projeto pré-definido do programa PT06 EEAGrants 2009-2014
2014-2015 – “Projeto Friesa: Modelação do efeito do frio extremo na mortalidade:primeiros passos para o desenvolvimento de um sistema de vigilância e alerta para as vagas de frio” IPMA e INSA - FCT projecto exploratórios 2013.
2013-2015 – “Estudo exploratório dos efeitos tóxicos de misturas de micotoxinas em alimentos para crianças e potencial impato na saúde”. PTDC/DTP-FTO/0417/2012; 
  

Publicações (Selecção das contribuições mais relevantes)

Julião M, Nunes B, Sobral MA, Dias D, Inocêncio I, Barbosa A. Is it useful to ask "Está deprimido?" ("Are you depressed?") to terminally-ill Portuguese patients? Results from outpatient research. Palliat Support Care. 2015 May 20:1-4. [Epub ahead of print] PubMed PMID: 25989708.

 

Lupsa IR, Nunes B, Ligocka D, Elena Gurzau A, Jakubowski M, Casteleyn L, Aerts D, Biot P, Den Hond E, Castaño A, Esteban M, Kolossa-Gehring M, Fiddicke U, Knudsen LE, Schoeters G, Fátima Reis M. Urinary cotinine levels and environmental tobacco smoke in mothers and children of Romania, Portugal and Poland within the European human biomonitoring pilot study. Environ Res. 2015 Apr 1. pii:S0013-9351(15)00096-1. doi: 10.1016/j.envres.2015.03.018. [Epub ahead of print]PubMed PMID: 25841796.
Molbak K, Espenhain L, Nielsen J, Tersago K, Bossuyt N, Denissov G, Baburin A, Virtanen M, Fouillet A, Sideroglou T, Gkolfinopoulou K, Paldy A, Bobvos J, van Asten L, de Lange M, Nunes B, da Silva S, Larrauri A, Gomez IL, Tsoumanis A, Junker C, Green H, Pebody R, McMenamin J, Reynolds A, Mazick A. Excess mortality  among the elderly in European countries, December 2014 to February 2015. Euro Surveill. 2015 Mar 19;20(11). pii: 21065. PubMed PMID: 25811643.
Gaio V, Picanço I, Nunes B, Fernandes A, Mendonça F, Horta Correia F, Beleza Á, Gil AP, Bourbon M, Vicente A, Matias Dias C, Barreto da Silva M. Pharmacogenetic profile of a South Portuguese population: results from the pilot study of the European Health Examination Survey in Portugal. Public Health Genomics. 2015;18(3):139-50. doi: 10.1159/000373920. Epub 2015 Mar 10. PubMed PMID: 25766488.
Shivaji T, Sousa Pinto C, San-Bento A, Oliveira Serra LA, Valente J, Machado J, Marques T, Carvalho L, Nogueira PJ, Nunes B, Vasconcelos P. A large community outbreak of Legionnaires disease in Vila Franca de Xira, Portugal, October to November 2014. Euro Surveill. 2014 Dec 18;19(50):20991. PubMed PMID: 25597540.
Julião M, Nunes B, Barbosa A. Dignity therapy and its effect on the survival of terminally ill portuguese patients. Psychother Psychosom. 2015;84(1):57-8. doi: 10.1159/000366207. Epub 2014 Dec 24. PubMed PMID: 25547879.
Gil AP, Kislaya I, Santos AJ, Nunes B, Nicolau R, Fernandes AA. Elder Abuse in Portugal: Findings From the First National Prevalence Study. J Elder Abuse Negl. 2014 Aug 14. [Epub ahead of print] PubMed PMID: 25122109.
Reis MF, Namorado S, Aguiar P, Precioso J, Nunes B, Veloso L, Santos S, Miguel JP. Patterns of adherence to and compliance with the Portuguese smoke-free law in the leisure-hospitality sector. PLoS One. 2014 Jul 18;9(7):e102421. doi: 10.1371/journal.pone.0102421. eCollection 2014. PubMed PMID: 25036725; PubMed
Nunes B, Machado A, Guiomar R, Pechirra P, Conde P, Cristovão P, Falcão I.Estimates of 2012/13 influenza vaccine effectiveness using the case test-negativecontrol design with different influenza negative control groups. Vaccine.2014Jul 31;32(35):4443-9. doi: 10.1016/j.vaccine.2014.06.053. Epub 2014 Jun 21.PubMed PMID: 24962756.
Julião M, Oliveira F, Nunes B, Vaz Carneiro A, Barbosa A. Efficacy of dignity therapy on depression and anxiety in Portuguese terminally ill patients: a phase II randomized controlled trial. J Palliat Med. 2014 Jun;17(6):688-95. doi:10.1089/jpm.2013.0567. Epub 2014 Apr 15. PubMed PMID: 24735024.
Kissling E, Valenciano M, Buchholz U, Larrauri A, Cohen JM, Nunes B, Rogalska J, Pitigoi D, Paradowska-Stankiewicz I, Reuss A, Jiménez-Jorge S, Daviaud I, Guiomar R, O'Donnell J, Necula G, Głuchowska M, Moren A. Influenza vaccine effectiveness estimates in Europe in a season with three influenza type/subtypes circulating: the I-MOVE multicentre case-control study, influenza season 2012/13. Euro Surveill, 2014 Feb 13; 19(6): pii 20701.
Gaio V, Nunes B, Fernandes A, Mendonça F, Horta Correia F, Beleza A, Gil AP, Bourbon M, Vicente A, Dias CM, Barreto da Silva M. Genetic variation at the CYP2C19 gene associated with metabolic syndrome susceptibility in a South Portuguese population: results from the pilot study of the European Health Examination Survey in Portugal. Diabetol Metab Syndr, 2014 Feb 18; 6(1): 23. doi: 10.1186/1758-5996-6-23.
Coelho A, Dias A, Morais A, Nunes B, Ferreira E, Picanço I, Faustino P, Lavinha J. Genetic variation in CD36, HBA, NOS3 and VCAM1 is associated with chronic haemolysis level in sickle cell anaemia: a longitudinal study. Eur JHaematol, 2014 Mar;92(3):237-43. doi: 10.1111/ejh.12226.
Pinto C, Nunes B, Branco MJ, Falcão MF. Trends in influenza vaccination coverage in Portugal from 1998 to 2010: effect of major pandemic threats. BMC Public Health, 2013; 13: 1130
Aguiar P, Nunes B. [Odds Ratio: Review about the Meaning of an Epidemiological Measure]. Acta Med Port. 2013 Sep-Oct;26(5):505-10. Epub 2013 Oct 31. Portuguese. PubMed PMID: 24192088.
Coelho A, Dias A, Morais A, Nunes B, Ferreira E, Picanço I, Faustino P, Lavinha J. Genetic variation in CD36, HBA, NOS3 and VCAM1 is associated with chronic haemolysis level in sickle cell anaemia: a longitudinal study. Eur JHaematol. 2013 Oct 29. doi: 10.1111/ejh.12226. [Epub ahead of print] PubMed PMID:24168396.
Julião M, Oliveira F, Nunes B, Barbosa A. Time and life perception in the terminally ill: its utility in screening for depression. J Palliat Med. 2013Nov;16(11):1433-7. doi: 10.1089/jpm.2013.0149. Epub 2013 Sep 28. PubMed PMID:24073720.
Julião M, Barbosa A, Oliveira F, Nunes B. Prevalence and factors associated with desire for death in patients with advanced disease: results from a Portuguese cross-sectional study. Psychosomatics, 2013
Kissling E, Valenciano M, Larrauri A, Oroszi B, Cohen JM, Nunes B, Pitigoi D, Rizzo C, Rebolledo J, Paradowska-Stankiewicz I, Jiménez-Jorge S, Horváth JK, Daviaud I, Guiomar R, Necula G, Bella A, O’Donnell J, Głuchowska M, Ciancio BC, Nicoll A, Moren A. Low and decreasing vaccine effectiveness against influenza A(H3) in 2011/12 among vaccination target groups in Europe: results from the I-MOVE multicentre case–control study . Euro Surveill. 2013;18(5):pii=20390. Available online: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=20390
Nunes B, Machado A, Pechirra P, Falcão I, Gonçalves P, Conde P, et al. Efectividade da vacina antigripal na época 2010-2011 em Portugal: resultados do projeto EuroEVA. Rev Port Med Geral Fam. 2012;28:271-84.
Nunes B, Natário I, Lucília Carvalho M. Nowcasting influenza epidemics using non-homogeneous hidden Markov models. Stat Med. 2012 Nov 5. doi: 10.1002/sim.5670. [Epub ahead of print] PubMed PMID: 23124850.
Nielsen J, Mazick A, Andrews N, Detsis M, Fenech TM, Flores VM, Foulliet A, Gergonne B, Green HK, Junker C, Nunes B, O'Donnell J, Oza A, Paldy A, Pebody R, Reynolds A, Sideroglou T, Snijders BE, Simon-Soria F, Uphoff H, VAN Asten L, Virtanen MJ, Wuillaume F, Mølbak K. Pooling European all-cause mortality: methodology and findings for the seasons 2008/2009 to 2010/2011. Epidemiol Infect. 2012 Nov 27:1-15. [Epub ahead of print] PubMed PMID: 23182146.
Froes F, Diniz A, Mesquita M, Serrado M, Nunes B. Hospital admissions of adults with community-acquired pneumonia in Portugal between 2000 and 2009. EurRespir J. 2012 Aug 9. [Epub ahead of print] PubMed PMID: 22878871.
Mazick A, Gergonne B, Nielsen J, Wuillaume F, Virtanen MJ, Fouillet A, Uphoff H, Sideroglou T, Paldy A, Oza A, Nunes B, Flores-Segovia VM, Junker C, McDonald SA, Green HK, Pebody R, Mølbak K. Excess mortality among the elderly in 12 European countries, February and March 2012. Euro Surveill. 2012 Apr 5;17(14). pii: 20138. PubMed PMID: 22516003.
Santo I, Azevedo J, Nunes B, Gomes JP, Borrego MJ. Partner notification for chlamydia trachomatis urogenital infections: eight years of patient referral experience in the major Portuguese sexually transmitted infections clinic, 2000-07. Int J STD AIDS. 2011 Oct;22(10):548-51. PubMed PMID: 21998173.
Kissling E, Valenciano M, Cohen JM, Oroszi B, Barret AS, Rizzo C, Stefanoff P, Nunes B, Pitigoi D, Larrauri A, Daviaud I, Horvath JK, O'Donnell J, Seyler T, Paradowska-Stankiewicz IA, Pechirra P, Ivanciuc AE, Jiménez-Jorge S, Savulescu C, Ciancio BC, Moren A. I-MOVE multi-centre case control study 2010-11: overall and stratified estimates of influenza vaccine effectiveness in Europe. PLoS One. 2011;6(11):e27622. Epub 2011 Nov 15. PubMed PMID: 22110695; PubMed Central PMCID:PMC3216983.
Nunes B, Viboud C, Machado A, Ringholz C, Rebelo-de-Andrade H, Nogueira P, Miller M. Excess mortality associated with influenza epidemics in Portugal, 1980 to 2004. PLoS One. 2011;6(6):e20661. Epub 2011 Jun 21.
Flasche S, Hens N, Boëlle PY, Mossong J, van Ballegooijen WM, Nunes B, Rizzo C, Popovici F, Santa-Olalla P, Hrubá F, Parmakova K, Baguelin M, van Hoek AJ, Desenclos JC, Bernillon P, Cámara AL, Wallinga J, Asikainen T, White PJ, Edmunds WJ. Different transmission patterns in the early stages of the influenza A(H1N1)v pandemic: a comparative analysis of 12 European countries. Epidemics. 2011 Jun;3(2):125-33. doi: 10.1016/j.epidem.2011.03.005. Epub 2011 Apr 13.
Valenciano M, Kissling E, Cohen JM, Oroszi B, Barret AS, Rizzo C, Nunes B, Pitigoi D, Larrauri Cámara A, Mosnier A, Horvath JK, O'Donnell J, Bella A, Guiomar R, Lupulescu E, Savulescu C, Ciancio BC, Kramarz P, Moren A. Estimates of Pandemic Influenza Vaccine Effectiveness in Europe, 2009-2010: Results of Influenza Monitoring Vaccine Effectiveness in Europe (I-MOVE) Multicentre Case-Control Study. PLoS Med. 2011 Jan;8(1):e1000388. Epub 2011 Jan 11.
Nunes B, Paixão E, Dias C, Nogueira P, Falcão JM. Air conditioning and intra-hospital mortality during the 2003 heat wave in Portugal: evidence of a protective effect. Occup Environ Med 2011;68:218-223 doi:10.1136/oem.2010.058396
Nogueira PJ, Machado A, Rodrigues E, Nunes B, Sousa L, Jacinto M, Ferreira A, Falcão JM, Ferrinho P. The new automated daily mortality surveillance system in Portugal. Euro Surveill. 2010 Apr 1;15(13).
Nunes B, Natário I, Carvalho ML. Time series methods for obtaining excess mortality attributable to influenza epidemics. Stat Methods Med Res. 2010 Mar 8. [Epub ahead of print]
Kissling E, Valenciano M, Falcao J, Larrauri A, Widgren K, Pitigoi D, Oroszi B, Nunes B, Savulescu C, Mazick A, Lupulescu E, Ciancio B, Moren A. effectiveness: lessons learnt from a pilot multi-centric case-control study in Europe, 2008-9. Euro Surveill. 2009 Nov 5;14(44).
Pádua E, Parreira R, Tendeiro R, Nunes B, Castela J, Soares I, Mouzinho A, Reis E, Paixão MT. Potential impact of viral load and genetic makeup of HIV type 1 on mother-to-child transmission: characterization of env-C2V3C3 and nef sequences. AIDS Res Hum Retroviruses. 2009 Nov;25(11):1171-7.
Nunes A, Borrego MJ, Nunes B, Florindo C, Gomes JP. Evolutionary dynamics of ompA, the gene encoding the Chlamydia trachomatis key antigen. J Bacteriol. 2009 Dec;191(23):7182-92. Epub 2009 Sep 25.
Nogueira PJ, Nunes B, Machado A, Rodrigues E, Gómez V, Sousa L, Falcão JM. Early estimates of the excess mortality associated with the 2008-9 influenza season in Portugal. Euro Surveill. 2009 May 7;14(18). pii: 19194.
Pádua E, Almeida C, Nunes B, Cortes Martins H, Castela J, Neves C, Paixão MT. Assessment of mother-to-child HIV-1 and HIV-2 transmission: an AIDS reference laboratory collaborative study. HIV Med. 2009 Mar;10(3):182-90. Epub 2009 Jan 7.
Nunes B, Pechirra P, Coelho A, Ribeiro C, Arraiolos A, Rebelo-de-Andrade H. Heterogeneous selective pressure acting on influenza B Victoria- and Yamagata-like hemagglutinins. J Mol Evol. 2008 Oct;67(4):427-35. Epub 2008 Oct 8
Oleastro M, Cordeiro R, Ferrand J, Nunes B, Lehours P, Carvalho-Oliveira I, Mendes AI, Penque D, Monteiro L, Mégraud F, Ménard A. Evaluation of the clinical significance of homB, a novel candidate marker of Helicobacter pylori strains associated with peptic ulcer disease.J Infect Dis. 2008 Nov 1;198(9):1379-87
Nunes B, Falcão I, Machado A, Rodrigues E, Marinho Falcão J. Euro Surveill 2007;12(5):E070517.2. Available from: http://www.eurosurveillance.org/ew/2007/070517.asp#2
Marinho Falcão I, Monsanto A, Nunes B, Marau J, Marinho Falcão J. Prescrição de psicofármacos em Medicina Geral e Familiar: um estudo da rede Médicos Sentinela. Revista Portuguesa de Clinica Geral. 2007, 23: 17-30
Nunes B, Falcão I, Machado A, Marinho Falcão J, Nogueira P, Rodrigues E, Paixão E. Cenários de impacto de uma eventual pandemia de gripe na população portuguesa: morbilidade, mortalidade e necessidade de cuidados de saúde Revista Portuguesa de Saúde Publica Vol 25 N 2, 2007
Nunes B, Branco MJ. Incidência de acidentes domésticos e de lazer no Continente, em 2002 Revista Portuguesa de Saúde Publica, Vol 24 N 2, 2006.
Pechirra P, Nunes B, Coelho A, Ribeiro C, Gonçalves P, Pedro S, Canto e Castro L, Rebelo-de-Andrade H. Molecular Characterization of the HA gene of Influenza type B viruses. Journal of Medical Virology. 77:541-549 2005 Wiley-Liss, Inc
Batista R, Nunes B, Carmo M, Cardoso C, São José H, Bugalho de Almeida A, Manique A, Bento L, Pinto Ricardo C, and Oliveira MM. Lack of detectable allergenicity of transgenic maize and soya samples. Journal of Allergy and Clinical Imunology. 403-410. August 2005.
Nunes B, Contreiras T, Marinho Falcão J. Vacinação anti-gripal: cobertura da população portuguesa entre 1998/1999 e 2002/2003. Revista Portuguesa de Pneumologia. Abril/Março 2004. X(2) 115-123
Caniça M, Dias R, Nunes B, Carvalho L, Ferreira E; Meningococci Study Group. Invasive culture-confirmed Neisseria meningitidis in Portugal: evaluation of serogroups in relation to different variables and antimicrobial susceptibility (2000-2001).J Med Microbiol. 2004 Sep;53(Pt 9):921-5.

Nogueira PJ, Nunes B, Matias Dias C, Marinho Falcão J. Um sistema de vigilância e alerta de ondas de calor com efeitos na mortalidade; o índice Icaro. Revista de Saúde Publica, Número temático:1, 1999.

 

Outros dados curriculares (C.V.)

Coordenador da Unidade de Investigação Epidemiológica do Departamento de Epidemiologia do Instituto Nacional de Saúde Doutor Ricardo Jorge

Investigador Auxiliar do Departamento de Epidemiologia do Instituto Nacional de Saúde Dr. Ricardo Jorge
Doutor em Probabilidades e Estatística (Faculdade de Ciências da Universidade de Lisboa, 2012).
Mestrado em Probabilidades e Estatística (Faculdade de Ciências de Lisboa, 2003).
Licenciatura em Matemática Aplicada ramo Estatística e Investigação Operacional (Faculdade de Ciências de Lisboa, 1997).

Atividades como revisor: PLosONE ; Revista Portuguesa de Saúde Pública; BMC Public Health; Biometrics; Epidemiology and Infection; Eurosurveillance; Environmental Perspectives ; Emerging Infectious Diseases; Journal of Infectious Diseases; Vaccine; Ata Pediátrica (revisor de Estatística e epidemiologia) Revista Portuguesa de Medicina Geral e Familiar (revisor de Estatística e epidemiologia).