Corpo Docente

Staff

Pedro Laires

Epidemiologia e Estatística Professor Auxiliar Convidado

Colaboração

Professor Auxiliar Convidado na área da Epidemiologia e membro do Centro de Investigação em Saúde Pública.

Mestre e Doutor em Epidemiologia pela Faculdade de Medicina da Universidade de Lisboa. PosDoc na ENSP-NOVA.

Autor de mais de 40 publicações em revistas científicas indexadas e mais de 200 comunicações em congressos nacionais e internacionais. Os seus principais interesses de investigação são a epidemiologia, a avaliação económica, e a avaliação de resultados em saúde (outcomes research). É Diretor Global de Epidemiologia (Real-World Evidence) da Novartis. Especialista na área de Outcomes Research onde tem vindo a desenvolver investigação nos últimos 15 anos, tanto ao nível académico como na indústria farmacêutica.

Coordenação do Curso de curta duração em Outcomes Research.

Seminário de Epidemiologia do Doutoramento em Saúde Pública.

Projeto sobre o impacto da multimorbilidade na reforma antecipada.

Estudos de Efectividade de medicamentos (farmacoepidemiologia)

Estudos Epidemiológicos (e.g. EpiReumaPt)

Lidera e colabora em diversos projetos de Health Economics & Outcomes Research (HEOR) e de Real-World Evidence (RWE).

Laires PA, Dias S, Gama A, Moniz M, Pedro AR, Soares P, Aguiar P, Nunes C.  The Association Between Chronic Disease and Serious COVID-19 Outcomes and Its Role on Risk Perception: Survey Study.  JMIR Public Health & Surveillance in press Jan 2021

 Laires PA, Nunes C.  Population-based Estimates for High Risk of Severe COVID-19 Disease due to Age and Underlying Health Conditions.  Acta Med Port. 2020 Nov 2;33(11):720-725.

Ferreira JP, Araújo F, Dores J, Santos L, Pape E, Reis M, Chipepo Á, Nascimento E, Baptista A, Pires V, Marques C, Lages AS, Conceição J, Laires PA, Pelicano-Romano J, Alão S.  Hospitalization Costs Due to Hypoglycemia in Patients with Diabetes: A Microcosting Approach.  Diabetes Ther. 2020  Oct;11(10):2237-2255.

Laires PA, Carrilho M, Tavares-Costa J, Lucas P, Machado P, Cunha-Miranda L, Pimentel-Santos F, Santos H, Vieira-Sousa E, Santos MJ .  Development and validation of psoriatic arthritis switch quality assessment tool (PASQAL) - an outcomes measurement tool to assess the quality of biologic switch decisions in psoriatic arthritis. Acta Reumatol Port. 2020 Jan-Mar;45(1):46-57.

 Laires PA, Serrano-Alarcón M, Canhão H, Perelman J.  Multimorbidity and intention to retire: a cross-sectional study on 14 European countries.  Int J Public Health. 2019 Dec 20

Borges M, Afonso-Silva M, Laires PA, Gouveia M, Alarcão J, Ascenção R, Costa J. Cost-effectiveness of sacubitril/valsartan for the treatment of patients with heart failure with reduced ejection fraction in Portugal.  Expert Rev Pharmacoecon Outcomes Res. 2019 Jun 20:1-7

 Laires PA, Perelman J.  The Current and Projected Burden of Multimorbidity: A Cross-Sectional Study in a Southern-Europe Population.  Eur J Ageing. 2018 Sep 1;16(2):181-192.  (Awarded with Best Annual Publication on Epidemiology by APE)

Macieira C, Cunha-Miranda L, Nero P, Laires PA, Bogas M, Farinha S, Freitas I, Lucas P, Sousa J, Narciso L, Mateus E, Canas da Silva J, Fonseca JE, Study Group RS.  Rheuma SPACE - Standard Practice Aiming Clinical Excellence: description of the methodological approach.  Acta Reumatol Port. 2019 Sep 8

Torre C, Guerreiro JP, Romano S, Miranda A, Longo P, Alão S, Conceição J, Laires PA.  Real-World Prevalence of Mild to Moderate Hypoglycemic Episodes in Portugal: Results from the HIPOS-PHARMA Study.  Primary Care Diabetes. 2018 Sep 12(6):537-546

 Laires PA, Kurtyka K, Witt EA, Qiu Y , Yu S, Iglay K.  Factors associated with physicians’ decision to discontinue or down-titrate sulfonylureas for type 2 diabetes patients. Expert Rev Pharmacoecon Outcomes Res. 2018 Sep 26:1-9

Laires PA, Mourão AF, Ribeiro C, Borges J, Gonçalves MJ, Bernardes M, Fernandes S, Dezerto R, Mesquita R, Ferreira J, Machado P, Eusebio M, Santos MJ, Canhão H.  Real-World Quality-Adjusted Life-Years Gains in Portuguese Patients with Rheumatoid Arthritis treated with Golimumab. Advances in Rheumatology (submitted)

 Laires PA, Canhão H, Rodrigues AM, Eusébio M, Gouveia M, Branco JC.  The impact of osteoarthritis on early exit from work: results from a population-based study.  BMC Public Health. 2018 Apr 11;18(1):472

Fonseca JE, Pereira da Silva JA, Bernardes M, Cernadas R, Canas da Silva J, Costa L, Videira T, C Miranda L, Barcelos A, Laires PA, Dezerto R, D Pereira M, Vidal F, Cunha E, Morais A, Martins C, Mesquita R.  Effectiveness of a Referral Program for rheumatoid arthritis and axial spondyloarthritis Diagnosis at Primary Care Centers in Portugal – SIARA STUDY.  Acta Reumatol Port. 2018 Jan-Mar;43(1):40-51

Conceição J, Dores J, Araújo F, Laires PA, Carr RD, Brodovicz K, Radican L, Nogueira AM. Severe hypoglycaemia among patients with type 2 diabetes requiring emergency hospital admission: The Hypoglycaemia In Portugal Observational Study-Emergency Room (HIPOS-ER).  Diabetes Obes Metab. 2018 Jan;20(1):50-59

Conceição J, Dores J, Araújo F, Laires PA, Carr RD, Brodovicz K, Radican L, Nogueira AM.  Severe hypoglycaemia among patients with type 2 diabetes requiring emergency hospital admission: The Hypoglycaemia In Portugal Observational Study-Emergency Room (HIPOS-ER). Diabetes Obes Metab. 2018 Jan;20(1):50-59

Silva Miguel L, Vargas Lopes F, Pinheiro B, Wang J, Xu R, Pellissier J, Laires PA.  Cost-Effectiveness of Pembrolizumab for advanced melanoma treatment in Portugal.  Value Health. 2017 Sep;20(8):1065-1073

 Laires PA, Gouveia M, Canhão H.Interventions aiming to reduce early retirement due to rheumatic diseases. Acta Reumatol Port. 2017 Jul-Sep;42(3):240-248

Laires PA, Barros V. RegisPt: Registry of Registries in Portugal – Design, Data Model, and Functionalities

Port J Public Health 2017;35:126–131

Mourão AF, Ribeiro C, Borges J, Gonçalves MJ, Bernardes M, Fernandes S, Dezerto R, Laires PA, Machado P, Eusébio M, Santos MJ, Canhão H. Real-life effectiveness of Golimumab in biologic-naïve patients with rheumatoid arthritis - data from the Rheumatic Diseases Portuguese Register (Reuma.pt).

Acta Reumatol Port. 2017 Jun;42(Apr-Jun):141-149

Laires PA, Gouveia M, Canhão H, Branco JC. The Economic Impact of Early Retirement Caused by Rheumatic Diseases - Results from a Nationwide Epidemiologic Study. Public Health. 2016 Nov;140:151-162

Laires PA, Laíns J, Miranda LC, Cernadas R, Rajagopalan S, Taylor SD, Silva JC. Inadequate Pain Relief Among Patients with Primary Knee Osteoarthritis. Rev Bras Reumatol Engl Ed. 2017 May - Jun;57(3):229-237

Laires PA, Inês M, Gouveia M, Mateus C, Miguel LS, Pinto CG.  The Challenges about Health Technology Reassessment in Portugal.  Rev Port Farm Sep 2016.

Laires PA, Tang J, Fan CP, Li Z, Qiu Y, Iglay K. Impact of Hypoglycemic Events and HbA1c Level on Sulfonylurea Discontinuation and Down-titration. Expert Rev Pharmacoecon Outcomes Res. 2016 Jun 30:1-8.

 Laires PA, Conceição J, Araújo F, Dores J, Silva C, Radican L, Nogueira A.  The Cost of Managing Severe Hypoglycemic Episodes in Type 2 Diabetic Patients. Expert Rev Pharmacoecon Outcomes Res. 2016 Apr;16(2):315-25.

Iglay K, Qiu Y, Fan CPS, Li Z, Tang J, Laires PA.  Risk factors associated with treatment discontinuation and down-titration in type 2 diabetes patients treated with sulfonylureas. Curr Med Res Opin. 2016 Sep;32(9):1567-75.

Branco JC, Rodrigues AM, Gouveia N, Eusébio M, Ramiro S, Machado PM, da Costa LP, Mourão AF, Silva I, Laires PA, Sepriano A, Araújo F, Gonçalves S, Coelho PS, Tavares V, Cerol J, Mendes JM, Carmona L, Canhão H.  Prevalence of rheumatic and musculoskeletal diseases and their impact on health-related quality of life, physical function and mental health in Portugal: results from EpiReumaPt- a national health survey.  RMD Open. 2016 Jan 19;2(1).

 Laires PA, Perelman J, Consciência JG, Monteiro J, Branco JC.  Epidemiology of hip fractures and its social and economic impact. An update for 2014.  Acta Reumatol Port. 2015 Jul-Sep;40(3):223-30.

Rodrigues AM, Gouveia N, da Costa LP, Eusébio M, Ramiro S, Machado P, Mourão AF, Silva I, Laires PA, Sepriano A, Araújo F, Coelho PS, Gonçalves S, Zhao A, Fonseca JE, de Almeida JM, Tavares V, da Silva JA, Barros H, Cerol J, Mendes J, Carmona L, Canhão H, Branco JC.  EpiReumaPt- the study of rheumatic and musculoskeletal diseases in Portugal: a detailed view of the methodology.  Acta Reumatol Port. 2015 Apr-Jun;40(2):110-24.

Gouveia N, Rodrigues AM, Ramiro S, Machado P, da Costa LP, Mourão AF, Silva I, Rego T, Laires PA, André R, Mauricio L, Romeu JC, Tavares V, Cerol J, Canhão H, Branco JC.  EpiReumaPt: how to perform a national population based study - a practical guide.  Acta Reumatol Port. 2015 Apr-Jun;40(2):128-36.

Laires PA, Ejzykowicz F, Davies G, Ambegaonkar B, Hsu TY.  Cost-Effectiveness of adding Ezetimibe to Atorvastatin therapy in Portugal.  J Med Econ. 2015 Apr 10:1-8.

 Laires PA, Perelman J, Consciência JG, Monteiro J, Branco JC.  Epidemiology of hip fractures and its social and economic impact. An update for 2014.  Acta Reumatol Port. 2015 Feb 2

Laires PA, Canhão H, Gouveia M.  Indirect Costs Associated with Early Exit from Work Attributable to Rheumatic Diseases.  Eur J Public Health. 2015 Jan 28

 Laires PA, Gouveia M.  Association of rheumatic diseases with early exit from paid employment in Portugal.  Rheumatol Int. 2014 Apr;34(4):491-501

 Laires PA, Mesquita R, Veloso L, Martins AP, Cernadas R, Fonseca JE. Patient's access to biologics in rheumatoid arthritis: the views of healthcare stakeholders in Portugal.  BMC Musculoskelet Disord. 2013 Sep 25;14(1):279 (Highly Accessed)

Elbasha EH, Chhatwal J, Ferrante SA, El Khoury AC, Laires PA.  Cost-Effectiveness Analysis of Boceprevir for the Treatment of Chronic Hepatitis C Virus Genotype 1Infection in Portugal.  Appl Health Econ Health Policy. Feb 2013;11(1):65-78

 Laires PA, Exposto F, Mesquita R, Miranda L, Fonseca JE.  Patients' access to biologics in rheumatoid arthritis: A comparison between Portugal and other European countries.  Eur J Health Econ. 2013 Dec;14(6):875-85

Gouveia M, Laires PA, Borges M, Augusto M, Martins AP.  Antidiabéticos Orais e Internamentos Atribuíveis à Diabetes em Portugal.  Acta Médica Portuguesa, Sep 2012;25(5):323-31

 Laires PA, Canhão H, Araújo D, Fonseca JE, Machado P, Mourão AF, Ramiro S, Romeu JC, Santos MJ, Silva I, Silva JAP, Sousa E, Tavares V, Gouveia N, Branco JC.  CoReumaPt Protocol - The Portuguese Cohort of Rheumatic Diseases.  Acta Reumatol Port. 2012;37:18-24

Solá S, Castro RE, Laires PA, Steer CJ, Rodrigues CMP.  Tauroursodeoxycholic Acid Prevents Amyloid-beta Peptide-Induced Neuronal Death Via a Phosphatidylinositol 3-Kinase-Dependent Signaling Pathway. Mol Med. 2003; 9: 226-234

Rodrigues CMP, Solá S, Castro RE, Laires PA, Brites D, Moura JJG. Perturbation of membrane dynamics in nerve cells as an early event during bilirubin-induced apoptosis.  Journal of Lipid Research 2002; 43: 885-894

Solá S, Castro RE, Laires PA, Rodrigues CMP.  Apoptose e lesão hepática.  Journal Português de  Gastroenterologia 2002.

 

 

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Diretor Global de Epidemiologia (Real-World Evidence) da Novartis